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1

Characterising the Binding Specificities of the Subunits Associated with the KMT2/Set1 Histone Lysine Methyltransferase

Ben L. Murton, Wee Loong Chin, Chris P. Ponting, Laura S. Itzhaki

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 780 KB

english, 2010

2

Programmed protein self-assembly driven by genetically encoded intein-mediated native chemical ligation

Harvey, Joseph A, Itzhaki, Laura S., Main, Ewan

Journal:

ACS Synthetic Biology

Year:

2018

Language:

english

File:

PDF, 1.41 MB

english, 2018

3

Water-soluble, stable and azide-reactive strained dialkynes for biocompatible double strain-promoted click chemistry

Sharma, Krishna, Strizhak, Alexander V., Fowler, Elaine, Wang, Xuelu, Xu, Wenshu, Hatt, Claus, Wu, Yuteng, Sore, Hannah, Lau, Yu Heng, Hyvönen, Marko, Itzhaki, Laura, Spring, David R

Journal:

Organic & Biomolecular Chemistry

Year:

2019

Language:

english

File:

PDF, 1.18 MB

english, 2019

4

Nature and nurture in protein folding and binding

Laura Itzhaki, Peter Wolynes

Journal:

Current Opinion in Structural Biology

Year:

2010

Language:

english

File:

PDF, 79 KB

english, 2010

5

Functionalised staple linkages for modulating the cellular activity of stapled peptides

Lau, Yu Heng, de Andrade, Peterson, Quah, Soo-Tng, Rossmann, Maxim, Laraia, Luca, Sköld, Niklas, Sum, Tze Jing, Rowling, Pamela J. E., Joseph, Thomas L., Verma, Chandra, Hyvönen, Marko, Itzhaki, Laura

Journal:

Chemical Science

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

6

Complex Energy Landscape of a Giant Repeat Protein

Tsytlonok, Maksym, Craig, Patricio O., Sivertsson, Elin, Serquera, David, Perrett, Sarah, Best, Robert B., Wolynes, Peter G., Itzhaki, Laura S.

Journal:

Year:

2013

Language:

english

File:

PDF, 3.10 MB

english, 2013

7

Single-Molecule FRET Reveals Hidden Complexity in a Protein Energy Landscape

Tsytlonok, Maksym, Ibrahim, Shehu M., Rowling, Pamela J.E., Xu, Wenshu, Ruedas-Rama, Maria J., Orte, Angel, Klenerman, David, Itzhaki, Laura S.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.17 MB

english, 2015

8

Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase

Xu, Wenshu, Lau, Yu Heng, Fischer, Gerhard, Tan, Yaw Sing, Chattopadhyay, Anasuya, de la Roche, Marc, Hyvönen, Marko, Verma, Chandra, Spring, David R., Itzhaki, Laura S.

Journal:

Journal of the American Chemical Society

Year:

2017

Language:

english

File:

PDF, 15.71 MB

english, 2017

9

PyFolding : Open-Source Graphing, Simulation, and Analysis of the Biophysical Properties of Proteins

Lowe, Alan R., Perez-Riba, Albert, Itzhaki, Laura S., Main, Ewan R.G.

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

10

Nanoscale click-reactive scaffolds from peptide self-assembly

Guttenplan, Alexander P. M., Young, Laurence J., Matak-Vinkovic, Dijana, Kaminski, Clemens F., Knowles, Tuomas P. J., Itzhaki, Laura S.

Journal:

Journal of Nanobiotechnology

Year:

2017

Language:

english

File:

PDF, 2.67 MB

english, 2017

11

The AAA+ protease ClpXP can easily degrade a 31 and a 52-knotted protein

Sivertsson, Elin M., Jackson, Sophie E., Itzhaki, Laura S.

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 2.67 MB

english, 2019

12

A unique binding cavity for divalent cations in the DNA–metal–chromomycin A3 complex

Laura Itzhaki, Sarah Weinberger, Nurit Livnah, Elisha Berman

Journal:

Year:

1990

Language:

english

File:

PDF, 641 KB

english, 1990

13

Solvent isotope effects on the refolding kinetics of hen egg-white lysozyme

Laura S. Itzhaki, Philip A. Evans

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 775 KB

english, 1996

14

Alcohol oxidase (AOX1) from Pichia pastoris is a novel inhibitor of prion propagation and a potential ATPase

Hong Zhang, Harriët M. Loovers, Li-Qiong Xu, Mingzhu Wang, Pamela J. E. Rowling, Laura S. Itzhaki, Weimin Gong, Jun-Mei Zhou, Gary W. Jones, Sarah Perrett

Journal:

Molecular Microbiology

Year:

2009

Language:

english

File:

PDF, 661 KB

english, 2009

15

10.1038/nsb1001-888

Schymkowitz, Joost W.H., Rousseau, Frederic, Wilkinson, Hannah R., Friedler, Assaf, Itzhaki, Laura S.

Journal:

Natural Structural Biology

Year:

2001

Language:

english

File:

PDF, 703 KB

english, 2001

16

Cooperative organization in a macromolecular complex

Seeliger, Markus A, Breward, Sadie E, Friedler, Assaf, Schon, Oliver, Itzhaki, Laura S

Journal:

Natural Structural Biology

Year:

2003

Language:

english

File:

PDF, 674 KB

english, 2003

17

Erratum: Cooperative organization in a macromolecular complex

Seeliger, Markus A, Breward, Sadie E, Friedler, Assaf, Schon, Oliver, Itzhaki, Laura S

Journal:

Nature Structural and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 103 KB

english, 2004

18

Binding of EMSY to HP1β: implications for recruitment of HP1β and BS69

Itzhaki, Laura S, Ekblad, Caroline M S, Chavali, Gayatri B, Basu, Balaka P, Freund, Stefan M V, Veprintsev, Dmitry, Hughes-Davies, Luke, Kouzarides, Tony, Doherty, Aidan J

Journal:

Year:

2005

Language:

english

File:

PDF, 206 KB

english, 2005

19

Comparison of BRCT domains of BRCA1 and 53BP1: A biophysical analysis

Caroline M.S. Ekblad, Assaf Friedler, Dmitry Veprintsev, Richard L. Weinberg, Laura S. Itzhaki

Journal:

Protein Science

Year:

2004

Language:

english

File:

PDF, 322 KB

english, 2004

20

Using FlAsH To Probe Conformational Changes in a Large HEAT Repeat Protein

Maksym Tsytlonok, Dr. Laura S. Itzhaki

Journal:

Year:

2012

Language:

english

File:

PDF, 822 KB

english, 2012

21

Erratum to ‘Nature and nurture in protein folding and binding’ [Curr Opin Struct Biol 2010, 20:1–2]

Laura Itzhaki, Peter Wolynes

Journal:

Current Opinion in Structural Biology

Year:

2010

Language:

english

File:

PDF, 68 KB

english, 2010

22

Folding and binding: lingering questions, emerging answers

Laura S Itzhaki, George D Rose

Journal:

Current Opinion in Structural Biology

Year:

2012

Language:

english

File:

PDF, 159 KB

english, 2012

23

Hydrogen exchange at equilibrium: a short cut for analysing protein-folding pathways?

Jane Clarke, Laura S. Itzhaki, Alan R. Fersht

Journal:

Trends in Biochemical Sciences

Year:

1997

Language:

english

File:

PDF, 1.25 MB

english, 1997

24

A reply to Englander and Woodward

Jane Clarke, Laura S Itzhaki, Alan R Fersht

Journal:

Trends in Biochemical Sciences

Year:

1998

Language:

english

File:

PDF, 88 KB

english, 1998

25

The Structure of the Transition State for Folding of Domain-Swapped Dimeric p13suc1

Frederic Rousseau, Joost W.H. Schymkowitz, Hannah R. Wilkinson, Laura S. Itzhaki

Journal:

Year:

2002

Language:

english

File:

PDF, 203 KB

english, 2002

26

Sequential Unfolding of Ankyrin Repeats in Tumor Suppressor p16

Kit S Tang, Alan R Fersht, Laura S Itzhaki

Journal:

Year:

2003

Language:

english

File:

PDF, 150 KB

english, 2003

27

The Unfolding Story of Three-Dimensional Domain Swapping

Frederic Rousseau, Joost W.H. Schymkowitz, Laura S. Itzhaki

Journal:

Year:

2003

Language:

english

File:

PDF, 258 KB

english, 2003

28

Strain in the folding nucleus of chymotrypsin inhibitor 2

Andreas G Ladurner, Laura S Itzhaki, Alan R Fersht

Journal:

Folding and Design

Year:

1997

Language:

english

File:

PDF, 248 KB

english, 1997

29

The Structure of the Transition State for Folding of Chymotrypsin Inhibitor 2 Analysed by Protein Engineering Methods: Evidence for a Nucleation-condensation Mechanism for Protein Folding

Laura S. Itzhaki, Daniel E. Otzen, Alan R. Fersht

Journal:

Journal of Molecular Biology

Year:

1995

Language:

english

File:

PDF, 1.37 MB

english, 1995

30

Search for Nucleation Sites in Smaller Fragments of Chymotrypsin Inhibitor 2

Laura S. Itzhaki, José Luis Neira, Javier Ruiz-Sanz, Gonzalo de Prat Gay, Alan R. Fersht

Journal:

Journal of Molecular Biology

Year:

1995

Language:

english

File:

PDF, 1.13 MB

english, 1995

31

Structure of the Transition State for Folding of a Protein Derived from Experiment and Simulation

Valerie Daggett, Aijun Li, Laura S. Itzhaki, Daniel E. Otzen, Alan R. Fersht

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 1013 KB

english, 1996

32

Following co-operative formation of secondary and tertiary structure in a single protein module

José L. Neira, Laura S. Itzhaki, Andreas G. Ladurner, Ben Davis, Gonzalo de Prat Gay, Alan R. Fersht

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 369 KB

english, 1997

33

Hydrogen exchange in chymotrypsin inhibitor 2 probed by denaturants and temperature

Laura S. Itzhaki, José L. Neira, Alan R. Fersht

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 316 KB

english, 1997

34

Hydrogen exchange in chymotrypsin inhibitor 2 probed by mutagenesis

José L. Neira, Laura S. Itzhaki, Daniel E. Otzen, Ben Davis, Alan R. Fersht

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 362 KB

english, 1997

35

Complementation of peptide fragments of the single domain protein chymotrypsin inhibitor 2

Andreas G. Ladurner, Laura S. Itzhaki, Gonzalo de Prat Gay, Alan R. Fersht

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 330 KB

english, 1997

36

Stability and folding of the tumour suppressor protein p16

Kit S Tang, Benjamin J Guralnick, Wooi Koon Wang, Alan R Fersht, Laura S Itzhaki

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 395 KB

english, 1999

37

Crystal Structure of the ENT Domain of Human EMSY

Gayatri B. Chavali, Caroline M.S. Ekblad, Balaka P. Basu, Nigel C. Brissett, Dmitry Veprintsev, Luke Hughes-Davies, Tony Kouzarides, Laura S. Itzhaki, Aidan J. Doherty

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 427 KB

english, 2005

38

Domain Swapping in p13suc1 Results in Formation of Native-like, Cytotoxic Aggregates

Frederic Rousseau, Hannah Wilkinson, Josep Villanueva, Luis Serrano, Joost W.H. Schymkowitz, Laura S. Itzhaki

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 716 KB

english, 2006

39

Activation of Ubiquitin Ligase SCFSkp2 by Cks1: Insights from Hydrogen Exchange Mass Spectrometry

Zhong-ping Yao, Min Zhou, Sadie E. Kelly, Markus A. Seeliger, Carol V. Robinson, Laura S. Itzhaki

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 1.75 MB

english, 2006

40

Biophysical Characterisation of the Small Ankyrin Repeat Protein Myotrophin

Alan R. Lowe, Laura S. Itzhaki

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 776 KB

english, 2007

41

ATPase Site Architecture and Helicase Mechanism of an Archaeal MCM

Matthew J. Moreau, Adam T. McGeoch, Alan R. Lowe, Laura S. Itzhaki, Stephen D. Bell

Journal:

Year:

2007

Language:

english

File:

PDF, 1.02 MB

english, 2007

42

Hydrogen exchange and protein folding

Jane Clarke, Laura S Itzhaki

Journal:

Current Opinion in Structural Biology

Year:

1998

Language:

english

File:

PDF, 772 KB

english, 1998

43

Mechanical Unfolding of an Ankyrin Repeat Protein

Serquera, David, Lee, Whasil, Settanni, Giovanni, Marszalek, Piotr E., Paci, Emanuele, Itzhaki, Laura S.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 943 KB

english, 2010

44

The how’s and why’s of protein folding intermediates

Tsytlonok, Maksym, Itzhaki, Laura S.

Journal:

Archives of Biochemistry and Biophysics

Year:

2013

Language:

english

File:

PDF, 380 KB

english, 2013

45

Tandem-repeat proteins: regularity plus modularity equals design-ability

Javadi, Yalda, Itzhaki, Laura S

Journal:

Current Opinion in Structural Biology

Year:

2013

Language:

english

File:

PDF, 1.45 MB

english, 2013

46

Protein folding: When ribosomes pick the structure

Sivertsson, Elin M., Itzhaki, Laura S.

Journal:

Nature Chemistry

Year:

2014

Language:

english

File:

PDF, 869 KB

english, 2014

47

Synergy between Simulation and Experiment in Describing the Energy Landscape of Protein Folding

Andreas G. Ladurner, Laura S. Itzhaki, Valerie Daggett and Alan R. Fersht

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.47 MB

english, 1998

48

Movement of the position of the transition state in protein folding

Matouschek, Andreas, Otzen, Daniel E., Itzhaki, Laura S., Jackson, Sophie E., Fersht, Alan R.

Journal:

Year:

1995

Language:

english

File:

PDF, 737 KB

english, 1995

49

Subdomain Architecture and Stability of a Giant Repeat Protein

Tsytlonok, Maksym, Sormanni, Pietro, Rowling, Pamela J. E., Vendruscolo, Michele, Itzhaki, Laura S.

Journal:

Journal of Physical Chemistry B

Year:

2013

Language:

english

File:

PDF, 3.02 MB

english, 2013

50

Folding and Association of the Human Cell Cycle Regulatory Proteins ckshs1 and ckshs2 †

Seeliger, Markus A., Schymkowitz, Joost W. H., Rousseau, Frederic, Wilkinson, Hannah R., Itzhaki, Laura S.

Journal:

Year:

2002

Language:

english

File:

PDF, 345 KB

english, 2002